Polycystic ovarian syndrome (PCOS) affects about one in ten women globally, making it one of the most prevalent endocrine disorders. Its symptoms, such as insulin resistance, hirsutism, hyperandrogenism, and weight gain, vary widely among patients. Despite the variety of treatments available, including lifestyle changes, medications like insulin sensitizers, and surgeries, there is no definitive cure for PCOS. Treatments like ovarian drilling and cosmetic interventions may alleviate specific symptoms but fail to address the root causes. Additionally, psychological, and occupational stress, coupled with infertility, worsens the condition for many women. This complexity has prompted the exploration of new therapeutic options. Recent attention has turned to coumarins, natural compounds with potential benefits in managing PCOS due to their anti-inflammatory, anti-androgenic, and insulin-sensitizing properties. These properties suggest that coumarins, when combined with existing treatments, could offer more holistic management of PCOS. Future therapeutic strategies may also involve polyherbal formulations, which could lower costs, reduce side effects, and improve overall treatment outcomes by targeting multiple facets of PCOS. The inclusion of coumarins as a natural, widely available resource highlights the potential for developing novel treatments that integrate traditional herbal medicine with modern medical approaches.

Mrs. Rashmi Wani, Dr. Mushtaque Shaikh

PCOS, Hyperandrogenaemia, Insulin, Herbal, Nutraceuticals, Coumarin